Delphine was honored for her work on the role of the protein Tis11b/BRF1 that she had previously identified as a regulator of a factor involved in the formation of blood vessels (VEGF). In this work, she identifies Dll4, another regulator of this process, as a new target of Tis11b. The multi-target activity of Tis11b represents a particularly interesting therapeutic way to fight against the formation of tumor blood vessels.