Biology and Biotechnologies for Health Laboratory - UMR_S 1292 CEA/Inserm/UGA - Other news https://biosante-lab.fr/en/Pages/IMAC/Theses.aspx en-US https://biosante-lab.fr/en/SiteAssets/min_logo_Biosante.png Biology and Biotechnologies for Health Laboratory - UMR_S 1292 CEA/Inserm/UGA - Other news https://biosante-lab.fr/en Identification of sensitive and specific biomarkers for the prediction of the survival of patients with cancer https://biosante-lab.fr/en/Pages/Theses/2025/Dzenis-Koca.aspx Thesis defended on November 6, 2025, by Dzenis KOCA to obtain a doctorate from the University of Grenoble Alpes PhD defense;renal cancer;COL7A1;IMAC; Thu, 06 Nov 2025 11:00:00 GMT Analysis of single-cell microRNA-mRNA co-sequencing data and comparison of microRNA target prediction algorithms https://biosante-lab.fr/en/Pages/Theses/2025/Louise-Velut.aspx Thesis defended on October 2, 2025 by Louise VELUT to obtain a doctorate from the University of Grenoble Alpes - Specialization: MBS - Models, methods, and algorithms in biology, health, and the environment. IMAC;PhD defense;microRNA targets;single cell;sequencing;microRNA; Thu, 02 Oct 2025 10:00:00 GMT Metastatic Renal Cancer: Toward a Microfluidic Chip Model to Study Intravasation and Tropism for a Bone Metastatic Niche https://biosante-lab.fr/en/Pages/Theses/2025/Beatrice-Cesana.aspx Thesis defended on September 17, 2025, by Beatrice Cesana to obtain a doctorate from the University of Grenoble Alpes - Specialization: Cell Biology. IMAC;PhD defense;kidney cancer;Medical device;tumoroid;microfluidic device; Wed, 17 Sep 2025 10:00:00 GMT Biophysical analysis of extracellular vesicles for diagnostics and precision medicine https://biosante-lab.fr/en/Pages/Theses/2023/Katell-Aldrin.aspx Thesis presented December 20, 2023 by Katell Aldrin. IMAC;microfluidics;PhD defense;extracellular vesicles; Wed, 20 Dec 2023 11:00:00 GMT Metastatic kidney cancer: Study of the mechanistics of a targeted combinational therapy and development of avatars for personalized medicine https://biosante-lab.fr/en/Pages/Theses/2023/Irinka-Seraudie.aspx Thesis presented February 20, 2023 by Irinka Seraudie. PhD thesis available as a pdf file. ROS;CRCC;CK2;IMAC;ATM;PhD defense;kidney cancer;organoids;tumoroid;Apoptosis; Mon, 20 Feb 2023 11:00:00 GMT Impact of activation of the Wnt/Beta-Catenin signaling pathway on the expression of microRNAs in adrenocortical carcinoma https://biosante-lab.fr/en/Pages/Theses/2022/Justine-Cristante.aspx Thesis presented November 10, 2022 by Justine Cristante. PhD thesis available as a pdf file. miR-139-5p;pronostique;IMAC;PhD defense;Adrenocortical carcinoma;prognosis;miRNA; Thu, 10 Nov 2022 11:00:00 GMT Development of an anti-cancer strategy for adrenocortical carcinoma by nanovectorization of microRNAs via Lipidots® https://biosante-lab.fr/en/Pages/Theses/2022/Soha-Reda-El-Sayed.aspx Thesis presented March 25, 2022 by Soha Reda El Sayed. PhD thesis available as a pdf file. miR-483-5p;miR-139-5p;IMAC;miRNA;Adrenocortical carcinoma;PhD defense; Fri, 25 Mar 2022 11:00:00 GMT Evaluation of different variants of the Cox model for cancer patients prognosis from public sequencing and clinical data https://biosante-lab.fr/en/Pages/Theses/2020/Remy-Jardillier.aspx Thesis presented December 01, 2020 by Rémy Jardillier. PhD thesis available as a pdf file. IMAC;PhD defense; Tue, 01 Dec 2020 11:00:00 GMT Applications in Bioinformatics with Markov Models https://biosante-lab.fr/en/Pages/Theses/2018/Sean-Robinson.aspx Thesis presented June 1st, 2018 by Sean Robinson. PhD thesis available as a pdf file. PhD defense;IMAC; Fri, 01 Jun 2018 10:00:00 GMT Protein kinases and renal carcinoma: Discovery and validation of a novel combinational target therapy through co-inhibition of CK2 and ATM kinases https://biosante-lab.fr/en/Pages/Theses/2016/Sofia-Giacosa.aspx Thesis presented October 14, 2016 by Sofia Giacosa. PhD thesis available as a pdf file. screening;spheroid;renal cancer;siRNA;3D culture;pharmacology;CK2;IMAC;PhD defense; Fri, 14 Oct 2016 10:00:00 GMT A novel multi-target cancer therapy based on destabilization of short-lived mRNAs https://biosante-lab.fr/en/Pages/Theses/2014/Felicitas-Rataj.aspx Thesis presented December​ 12, 2014 by Felicitas Rataj. PhD thesis available as a pdf file. Tis11B;IMAC;VEGF;Angiogenesis;mRNA;PhD defense;cancer therapy; Fri, 12 Dec 2014 11:00:00 GMT Regulation of SNAIL1 transcription factor during Epithelial-Mesenchymal Transition in MCF10A mammary cells: Involvement of protein-kinase CK2 https://biosante-lab.fr/en/Pages/Theses/2010/Alexandre-Deshiere.aspx Thesis presented November 09, 2010 by Alexandre Deshière. PhD thesis available as a pdf file. EMT;CK2;IMAC;siRNA;PhD defense; Tue, 09 Nov 2010 11:00:00 GMT Identification and characterization of protein kinase CK2 inhibitors https://biosante-lab.fr/en/Pages/Theses/2009/Renaud-Prudent.aspx Thesis presented November 23, 2009 by Renaud Prudent. CK2;IMAC;pharmacology;screening;PhD defense;inhibitor peptide; Mon, 23 Nov 2009 11:00:00 GMT Protein transduction domain-mediated intracellular delivery of the TTP family member TIS11b/BRF1 downregulates VEGF expression in vitro and in vivo https://biosante-lab.fr/en/Pages/Theses/2008/Severine-Planel.aspx Thesis presented November 17, 2008 by Séverine Planel. PhD thesis available as a pdf file. VEGF;Tis11B;IMAC;adrenocortical tumorigenesis;PhD defense;zinc fingers;cancer therapy; Mon, 17 Nov 2008 11:00:00 GMT Functional study of the regulating subunit of the protein kinase CK2 in murin embryonic stem cells: Cellular survival, oligodendrogenesis and cancerogenesis https://biosante-lab.fr/en/Pages/Theses/2007/Lea-Ziercher.aspx Thesis presented October 11, 2007 by Léa Ziercher. PhD thesis available as a pdf file. CK2;IMAC;PhD defense;stem cell; Thu, 11 Oct 2007 10:00:00 GMT Strategies for inhibiting high affinity protein-protein interaction: Example of CK2 https://biosante-lab.fr/en/Pages/Theses/2007/Beatrice-Laudet.aspx Thesis presented October 05, 2007 by Béatrice Laudet. PhD thesis available as a pdf file. CK2;IMAC;PhD defense;pharmacology; Fri, 05 Oct 2007 10:00:00 GMT Implication of protein kinase CK2 in the response to cellular stress. Study of the regulatory mechanisms involved in the regulation of CK2 https://biosante-lab.fr/en/Pages/Theses/2000/Delphine-Gerber-Scokaert.aspx Thesis presented October 20, 2000 by Delphine Gerber-Scokaert. PhD thesis available in Intranet as a pdf file. CK2;IMAC;PhD defense; Fri, 20 Oct 2000 10:00:00 GMT